Methylcobalamin, the active form of vitamin B12
has been known to help:
ADHD symptoms
Memory
Anxiety
Chronic fatigue
Dyslexia
Depth Perception
Viewing Color
Speech (finding words, apraxia, articulation, etc)
Socialization
Mood
Behavior
Sleep Regulation
Depression
Neurotransmitter function
Autoimmune symptoms
Chemical Sensitivity
Digestion
Viral Infections
Inflammatory conditions like rheumatoid arthritis, sciatica,
.....fibromyalgia
Asthma
Irritable bowel
Colitis
Eye or muscle "twittering"
Tinnitus
Nail bitting
Migraines
Visual and auditory processing
Modulation of light
Night vision
Improved ability to process sounds and modulate background
.....noise
Nerve regeneration
Blocking the effects of ethanol
Greatly reduces the desire for alcohol, marijuana,
.....methamphetamines, and possibly other addictive drugs and
.....behavior.
has been known to help:
ADHD symptoms
Memory
Anxiety
Chronic fatigue
Dyslexia
Depth Perception
Viewing Color
Speech (finding words, apraxia, articulation, etc)
Socialization
Mood
Behavior
Sleep Regulation
Depression
Neurotransmitter function
Autoimmune symptoms
Chemical Sensitivity
Digestion
Viral Infections
Inflammatory conditions like rheumatoid arthritis, sciatica,
.....fibromyalgia
Asthma
Irritable bowel
Colitis
Eye or muscle "twittering"
Tinnitus
Nail bitting
Migraines
Visual and auditory processing
Modulation of light
Night vision
Improved ability to process sounds and modulate background
.....noise
Nerve regeneration
Blocking the effects of ethanol
Greatly reduces the desire for alcohol, marijuana,
.....methamphetamines, and possibly other addictive drugs and
.....behavior.
| Learning to recognize signs of low B12 in your body is your BEST DEFENSE against the ravages of B12 Malabsorption Illness. |
While expensive tests are developed to test for B12 deficiency, as for
instance using a determination of holotranscobalamin, the transport
protein with selectively bound active cobalamin . . .
instance using a determination of holotranscobalamin, the transport
protein with selectively bound active cobalamin . . .
Symptoms of B12 Deficiency - health boundaries that bite
Too little stomach acid and B12
remains trapped in protein.
remains trapped in protein.
When there is adequate
stomach acid vitamin B12
is released from protein.
stomach acid vitamin B12
is released from protein.
You need intrinsic factor
before vitamin B12 can be
used by your body.
before vitamin B12 can be
used by your body.
Neurological symptoms:
Numbness in hands and feet
Ataxia (irregularity of muscular action)
Impaired reflexes
Gait disturbances (for instance difficulty walking a straight line)
Impaired vibration perception
Positive Romberg´s test:
Chronic fatigue syndrome/fibromyalgia
Psychiatric symptoms:
Concentration difficulties
Confusion
Irritation
Impaired memory and memory loss
Dementia
Irritability
Depression
Personality changes
Psychosis:
.....gross impairment in reality testing
.....evidenced by delusions
Symptoms of anaemia:
Tiredness
Apathy
Dyspnoea upon exertion:
.....Shortness of breath,
.....difficult or laboured breathing.
Other symptoms
Aversion to meat
Impotence
Faecal/urinary incontinence
Infertility
Vitiligo:
.....nonpigmented white patches of skin
Diarrhea
Hair loss
Numbness in hands and feet
Ataxia (irregularity of muscular action)
Impaired reflexes
Gait disturbances (for instance difficulty walking a straight line)
Impaired vibration perception
Positive Romberg´s test:
- closing the eyes increases unsteadiness;.indicates loss of
proprioceptive control (Proprioceptive: able to receive.
stimuli from muscles, etc.) Try closing your eyes and
turning in a circle - losing your balance indicates low B12
- Extension of the great toe and abduction of the other toes.
instead of normal reflex to plantar (sole of foot)
stimulation, considered indicative of pyramidal tract
involvement.(Pyramidal: anatomy: one of the carpal
bones.)
- Sudden electric-like shocks go down spine on flexing head
- wasting away or reduction from degeneration of nerve
fibres of optic nerve
Chronic fatigue syndrome/fibromyalgia
Psychiatric symptoms:
Concentration difficulties
Confusion
Irritation
Impaired memory and memory loss
Dementia
Irritability
Depression
Personality changes
Psychosis:
.....gross impairment in reality testing
.....evidenced by delusions
Symptoms of anaemia:
Tiredness
Apathy
Dyspnoea upon exertion:
.....Shortness of breath,
.....difficult or laboured breathing.
Other symptoms
Aversion to meat
Impotence
Faecal/urinary incontinence
Infertility
Vitiligo:
.....nonpigmented white patches of skin
Diarrhea
Hair loss
Symptoms of Vitamin B12 Deficiency
and Low Vitamin B12, and Conditions
Contributing to Low Vitamin B12
Not every one has the same symptoms of vitamin B12 deficiency.
You and your best friend may both be low in vitamin B12, but have
very different symptoms.
Because the symptoms of low vitamin B12 vary so much from
person to person the medical community has often concentrated on
one symptom and ignored others, with the result that many people
with severe symptoms of low B12 do not get treatment because they
don't have the symptom popular on a given day, the "symptom
d'jour" you might say.
Even today when there is more knowledge about vitamin B12 and its
symptoms, with a lot more research having been done to shed light on
the symptoms of vitamin B12 deficiency, there is still a tendency for
healthcare providers to do what they are familiar with from the past.
That might not be best for you if you have different symptoms than
your healthcare provider has commonly thought of for vitamin B12.
For example, even after I was diagnosed with "profound vitamin B12
deficiency" another doctor, one not at the hospital where I was
diagnosed, said that I couldn't have a vitamin B12 deficiency because
I wasn't a vegetarian. For that particular doctor, the first and most
important thing she looked for, to see if someone might be vitamin
B12 deficient, was a vegetarian diet.
So, anyone coming to her who wasn't a vegetarian wasn't going to
have their vitamin B12 level considered as a possible cause of any
negative health issues they might be experiencing.
Another example is more general and has to do with the fact that
there are two general categories of vitamin B12 deficiency symptoms:
those that are related to nerves, and those that are related to blood.
While it appears that a low vitamin B12 level if experienced over a
long time will inevitably lead to blood disorders, that is, to the blood
cells being too large, not everyone who initially has serious B12
problems will have the large blood cells associated with advanced
deficiency or the disease of pernicious anemia.
Because of the wide and confusing variety of low vitamin B12
symptoms, it is useful to look at your fingernails and see whether they
have ridges or are losing their moons. These simple signs show low
B12.
and Low Vitamin B12, and Conditions
Contributing to Low Vitamin B12
Not every one has the same symptoms of vitamin B12 deficiency.
You and your best friend may both be low in vitamin B12, but have
very different symptoms.
Because the symptoms of low vitamin B12 vary so much from
person to person the medical community has often concentrated on
one symptom and ignored others, with the result that many people
with severe symptoms of low B12 do not get treatment because they
don't have the symptom popular on a given day, the "symptom
d'jour" you might say.
Even today when there is more knowledge about vitamin B12 and its
symptoms, with a lot more research having been done to shed light on
the symptoms of vitamin B12 deficiency, there is still a tendency for
healthcare providers to do what they are familiar with from the past.
That might not be best for you if you have different symptoms than
your healthcare provider has commonly thought of for vitamin B12.
For example, even after I was diagnosed with "profound vitamin B12
deficiency" another doctor, one not at the hospital where I was
diagnosed, said that I couldn't have a vitamin B12 deficiency because
I wasn't a vegetarian. For that particular doctor, the first and most
important thing she looked for, to see if someone might be vitamin
B12 deficient, was a vegetarian diet.
So, anyone coming to her who wasn't a vegetarian wasn't going to
have their vitamin B12 level considered as a possible cause of any
negative health issues they might be experiencing.
Another example is more general and has to do with the fact that
there are two general categories of vitamin B12 deficiency symptoms:
those that are related to nerves, and those that are related to blood.
While it appears that a low vitamin B12 level if experienced over a
long time will inevitably lead to blood disorders, that is, to the blood
cells being too large, not everyone who initially has serious B12
problems will have the large blood cells associated with advanced
deficiency or the disease of pernicious anemia.
Because of the wide and confusing variety of low vitamin B12
symptoms, it is useful to look at your fingernails and see whether they
have ridges or are losing their moons. These simple signs show low
B12.
Low B12 and deficiency is often seen in:
Autoimmune diseases
Any person with:
inadequate nutrition
a smoking habit
high alcohol consumption
coping with significant stress
People complaining of:
Vertigo Asthenia
Loss of appetite
Loss of weight
Impaired memory
People who have had:
resection of stomach or ileum
stomach surgery
anaesthesia with nitrous oxide
adverse reactions to anaesthesia /surgery
People who use medicine affecting B12:
antacids: Prevacid, Prilosec, Tums, etc.
Omeprazole interferes w/B12 absorption from food
Metformin: drug used to treat diabetes
many antidepressants
Patients with Gastrointestinal disease:
Atrophy of the mucosa
Gluten-induced enteropathy
Crohn´s disease
Patients with Autoimmune diseases to include:
ALS - Lou Gehrig's Disease
Celiac Disease
Diabetes
Guillain-Barre Syndrome
Lupus
Multiple Sclerosis
Narcolepsy [
Rheumatoid arthritis
Hypothyroidism
Women:
following pregnancy complications
who produced an unusually large placenta
People with eating disorders:
Anorexia
Bulemia
People with marfanoid appearance
Vegans/vegetarians
Autoimmune diseases
Any person with:
inadequate nutrition
a smoking habit
high alcohol consumption
coping with significant stress
People complaining of:
Vertigo Asthenia
Loss of appetite
Loss of weight
Impaired memory
People who have had:
resection of stomach or ileum
stomach surgery
anaesthesia with nitrous oxide
adverse reactions to anaesthesia /surgery
People who use medicine affecting B12:
antacids: Prevacid, Prilosec, Tums, etc.
Omeprazole interferes w/B12 absorption from food
Metformin: drug used to treat diabetes
many antidepressants
Patients with Gastrointestinal disease:
Atrophy of the mucosa
Gluten-induced enteropathy
Crohn´s disease
Patients with Autoimmune diseases to include:
ALS - Lou Gehrig's Disease
Celiac Disease
Diabetes
Guillain-Barre Syndrome
Lupus
Multiple Sclerosis
Narcolepsy [
Rheumatoid arthritis
Hypothyroidism
Women:
following pregnancy complications
who produced an unusually large placenta
People with eating disorders:
Anorexia
Bulemia
People with marfanoid appearance
Vegans/vegetarians
If you have symptoms of low vitamin B12, then think
"Methylcobalamin" as you read: A Quick History of Vitamin
B12 (and look at the illustrations)
"Methylcobalamin" as you read: A Quick History of Vitamin
B12 (and look at the illustrations)
"Ask and you shall receive." So, please will you shop?
In 1997 the lines/ridges on my fingernails were the worst. I was unable to
think; things "looked" unclear; things seemed hopeless; I tried to kill
myself, and I had such horrible bone pain that it didn't seem like it would
make any difference if I immolated myself because of abuse by IRS. B12
changed all that!
think; things "looked" unclear; things seemed hopeless; I tried to kill
myself, and I had such horrible bone pain that it didn't seem like it would
make any difference if I immolated myself because of abuse by IRS. B12
changed all that!
http://www.health-boundaries-bite.com/Fingernails.html
Your fingernails reflect your health --
Learn some warning signs --
Karen Kline
Your fingernails reflect your health --
Learn some warning signs --
Karen Kline
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A Quick History of Vitamin B12
1850s -- English doctor, Thomas Addison, described a lethal "pernicious"
form of anemia, related to pathological gastric mucosa and associated with
the stomach having little or no acid.
1926 -- Georges Richard Minot and William Parry Murphy reported that
45 patients with pernicious anemia had been cured by eating large
quantities of raw liver.
1929 -- William Castle discovered that “intrinsic
factor” in the gastric mucosa was needed to absorb
liver's active ingredient, initially called “extrinsic
factor,” and that intrinsic factor was lacking in
pernicious anemia patients.
1934 -- Minot, Murphy and Whipple received
the Nobel Prize in Medicine for their
research isolating extrinsic factor
and identifying it as a vitamin.
1948 -- Pure vitamin B12 was produced.
1956 -- British chemist, Dorothy
Hodgkin, described the structure
of the B12 molecule.
1964 -- Dorothy Hodgkin received the Nobel Prize for Chemistry.
With knowledge of the B12 molecule, pernicious
anemia, once fatal, could be treated with
injectionsof vitamin B12, as cyanocobalamin,
and patients recovered.
Because blood cells in B12 deficient people were
often larger than normal blood cells, B12
deficiency was linked with the blood disorder,
anemia; the fact that B12 deficiency
was known to be accompanied by
nerve and neuropsychiatric problems
was overlooked. The governing belief
was that without anemia, there was no
B12 deficiency.
This inaccurate view is changing as new
markers are found. Two markers relating
to intracellular functional deficiency
are methylmalonic acid and homocysteine.
Today it is clear that anemia is only one of many different symptoms of
B12 deficiency. Pernicious anemia with its lack of intrinsic factor is now
thought to be relatively rare.
Hypochlorhydria, less familiar than pernicious
anemia, is the condition of not enough gastric acid
to separate vitamin B12 from food. An estimated
47% of people in the U.S. have hypochlorhydria,
partially due to increased use of antacids marketed
as a good source of calcium.
Research shows that smoking,
high alcohol consumption, and
many prescription drugs
reduce B12, as do some common genetic
polymorphisms (variations occurring within
a species) that affect enzyme activity.
For myself, I think that it may be the case
that high stress is the underlying problem
that reduces B12. It may be that people
smoke and drink to relieve stress because
they can feel the damage that the stress is doing. I'm not saying that
drinking and smoking are a cure for the problems arising from stress, I'm
saying that it's very possible that when stress is lowered and/or B12 levels
are increased there is less desire to smoke and drink, from a purely
physical level.
Through scientific testing over a long period it was learned that "functional
deficiency," that is, a deficient distribution of B12 at the cellular level,
could come about even though serum levels were normal.
Sadly, the American medical community sees fit to keep the "normal"
range extremely low, which fosters confusion and mis-diagnosis.
News reports during 2008 that linked doctor prescriptions with kick backs
from drug companies may make the medical community's favoritism for
drugs over nutrients less sad than criminal.
More about Symptoms of vitamin B12 deficiency
Initial symptoms of B12 deficiency are easily overlooked. Plus, early
symptoms of anemia may be masked by folic acid, or by an iron
deficiency. A variety of neuropsychiatric symptoms may be the earliest
and easily seen and felt symptoms.
The most common neurological symptoms in low vitamin B12 are
paraesthesia (numbness) of the hands and feet, diminished perception of
vibration and position, absence of reflexes, and unsteady gait and balance
-- the range of symptoms is broad.
Psychiatric symptoms seen in vitamin B12 deficiency are varied and fall
into several different categories:
Confusion and memory disturbances are the most common. Depression,
with or without psychotic components, and cognitive decline are frequent.
Swings in mood and personality changes from low B12, if untreated, may
become a psychiatric disease.
Such vague symptoms of vitamin B12 deficiency are easily overlooked,
especially as the serum concentration of vitamin B12 often lies within the
reference range. (In the United States the low for the reference range is
hundreds of points lower than the more realistic low in Japan and Europe.)
Disorders in the gastrointestinal tract can give rise to a deficiency of
vitamin B12, with symptoms being more or less pronounced. Poor
mucosal function may also be a cause and may show up with glossitis (a
swollen tongue).
The elderly are at great risk of vitamin B12 deficiency. Age-related, often
asymptomatic atrophic gastritis is common and may be enough to cause a
patient to slide slowly into a negative vitamin B12 balance with depleted
stores of the vitamin giving rise to dementia. (Because the low in the
United States is so low, this slide may go unnoticed for considerable
periods of time.)
Infants of vegetarian/vegan mothers are in danger of vitamin B12
deficiency, even though their mothers may not have B12 malabsorption
illness and may not show any deficiency symptoms. This is because of
the relatively high need for B12 in a rapidly growing child.
Finally, I repeat, if your fingernails have ridges or you are beginning to
lose the moons on your fingernails, please try Methylcobalamin and keep
notes and see if you begin to feel better with a reduction in symptoms you
may have found worrying and/or baffling. If you aren't going to go to
your healthfood store soon, please order Methylcobalamin on line.
form of anemia, related to pathological gastric mucosa and associated with
the stomach having little or no acid.
1926 -- Georges Richard Minot and William Parry Murphy reported that
45 patients with pernicious anemia had been cured by eating large
quantities of raw liver.
1929 -- William Castle discovered that “intrinsic
factor” in the gastric mucosa was needed to absorb
liver's active ingredient, initially called “extrinsic
factor,” and that intrinsic factor was lacking in
pernicious anemia patients.
1934 -- Minot, Murphy and Whipple received
the Nobel Prize in Medicine for their
research isolating extrinsic factor
and identifying it as a vitamin.
1948 -- Pure vitamin B12 was produced.
1956 -- British chemist, Dorothy
Hodgkin, described the structure
of the B12 molecule.
1964 -- Dorothy Hodgkin received the Nobel Prize for Chemistry.
With knowledge of the B12 molecule, pernicious
anemia, once fatal, could be treated with
injectionsof vitamin B12, as cyanocobalamin,
and patients recovered.
Because blood cells in B12 deficient people were
often larger than normal blood cells, B12
deficiency was linked with the blood disorder,
anemia; the fact that B12 deficiency
was known to be accompanied by
nerve and neuropsychiatric problems
was overlooked. The governing belief
was that without anemia, there was no
B12 deficiency.
This inaccurate view is changing as new
markers are found. Two markers relating
to intracellular functional deficiency
are methylmalonic acid and homocysteine.
Today it is clear that anemia is only one of many different symptoms of
B12 deficiency. Pernicious anemia with its lack of intrinsic factor is now
thought to be relatively rare.
Hypochlorhydria, less familiar than pernicious
anemia, is the condition of not enough gastric acid
to separate vitamin B12 from food. An estimated
47% of people in the U.S. have hypochlorhydria,
partially due to increased use of antacids marketed
as a good source of calcium.
Research shows that smoking,
high alcohol consumption, and
many prescription drugs
reduce B12, as do some common genetic
polymorphisms (variations occurring within
a species) that affect enzyme activity.
For myself, I think that it may be the case
that high stress is the underlying problem
that reduces B12. It may be that people
smoke and drink to relieve stress because
they can feel the damage that the stress is doing. I'm not saying that
drinking and smoking are a cure for the problems arising from stress, I'm
saying that it's very possible that when stress is lowered and/or B12 levels
are increased there is less desire to smoke and drink, from a purely
physical level.
Through scientific testing over a long period it was learned that "functional
deficiency," that is, a deficient distribution of B12 at the cellular level,
could come about even though serum levels were normal.
Sadly, the American medical community sees fit to keep the "normal"
range extremely low, which fosters confusion and mis-diagnosis.
News reports during 2008 that linked doctor prescriptions with kick backs
from drug companies may make the medical community's favoritism for
drugs over nutrients less sad than criminal.
More about Symptoms of vitamin B12 deficiency
Initial symptoms of B12 deficiency are easily overlooked. Plus, early
symptoms of anemia may be masked by folic acid, or by an iron
deficiency. A variety of neuropsychiatric symptoms may be the earliest
and easily seen and felt symptoms.
The most common neurological symptoms in low vitamin B12 are
paraesthesia (numbness) of the hands and feet, diminished perception of
vibration and position, absence of reflexes, and unsteady gait and balance
-- the range of symptoms is broad.
Psychiatric symptoms seen in vitamin B12 deficiency are varied and fall
into several different categories:
Confusion and memory disturbances are the most common. Depression,
with or without psychotic components, and cognitive decline are frequent.
Swings in mood and personality changes from low B12, if untreated, may
become a psychiatric disease.
Such vague symptoms of vitamin B12 deficiency are easily overlooked,
especially as the serum concentration of vitamin B12 often lies within the
reference range. (In the United States the low for the reference range is
hundreds of points lower than the more realistic low in Japan and Europe.)
Disorders in the gastrointestinal tract can give rise to a deficiency of
vitamin B12, with symptoms being more or less pronounced. Poor
mucosal function may also be a cause and may show up with glossitis (a
swollen tongue).
The elderly are at great risk of vitamin B12 deficiency. Age-related, often
asymptomatic atrophic gastritis is common and may be enough to cause a
patient to slide slowly into a negative vitamin B12 balance with depleted
stores of the vitamin giving rise to dementia. (Because the low in the
United States is so low, this slide may go unnoticed for considerable
periods of time.)
Infants of vegetarian/vegan mothers are in danger of vitamin B12
deficiency, even though their mothers may not have B12 malabsorption
illness and may not show any deficiency symptoms. This is because of
the relatively high need for B12 in a rapidly growing child.
Finally, I repeat, if your fingernails have ridges or you are beginning to
lose the moons on your fingernails, please try Methylcobalamin and keep
notes and see if you begin to feel better with a reduction in symptoms you
may have found worrying and/or baffling. If you aren't going to go to
your healthfood store soon, please order Methylcobalamin on line.
